43 research outputs found

    Atmospheric Temperature anomalies as manifestation of the dark Universe

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    We are investigating the possible origin of small-scale anomalies, like the annual stratospheric temperature anomalies. Unexpectedly within known physics, their observed planetary "dependency", does not match concurrent solar activity, whose impact on the atmosphere is unequivocal; this points at an additional energy source of exo-solar origin. A viable concept behind such observations is based on possible gravitational focusing by the Sun and its planets towards the Earth of low-speed invisible streaming matter; its influx towards the Earth gets temporally enhanced. Only a somehow "strongly" interacting invisible streaming matter with the small upper atmospheric screening can be behind the observed temperature excursions. Ordinary dark matter (DM) candidates like axions or WIMPs, cannot have any noticeable impact. The associated energy deposition is O(∼1000 GeV/cm2/sec)\mathcal{O}(\sim 1000\, \mathrm{GeV}/{{\mathrm{cm}}^2}/\mathrm{sec}). The atmosphere has been uninterruptedly monitored for decades. Therefore, the upper atmosphere can serve as a novel (low-threshold) detector for the dark Universe, with built-in spatiotemporal resolution while the solar system gravity acts temporally as a signal amplifier. Interestingly, the anomalous ionosphere shows a relationship with the inner earth activity like earthquakes. Similarly investigating the transient sudden stratospheric warmings within the same reasoning, the nature of the assumed "invisible streams" could be deciphered.Comment: 8 pages, 7 figures, Published in the proceedings of the "15th International Conference on Meteorology, Climatology and Atmospheric Physics (COMECAP 2021)" see https://www.conferre.gr/allevents/comecap2020/Proceedings_Final.pd

    Observations of quiet-time moderate midlatitude L-band scintillation in association with plasma bubbles

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    Observations of moderate night time amplitude scintillation on the GPS L1C/A signal were recorded at the midlatitude station of Nicosia, corresponding geographic latitude and longitude of 35.18˚N and 33.38˚E respectively, on a geomagnetically quiet day. The variations of slant total electron content (STEC) and amplitude scintillation index (S4) on the night of June 12, 2014, indicate the presence of electron density depletions accompanying scintillation occurrence. The estimated apparent horizontal drift velocity and propagation direction of the plasma depletions are consistent with those observed for the equatorial plasma bubbles, thus suggesting that the moderate amplitude L-band scintillation observed over Nicosia may be associated with the extension of such plasma bubbles. The L-band scintillation occurrence was concurrent with the observations of range spread F on the ionograms recorded by the digisonde at Nicosia. The height–time–intensity plot generated using the ionogram data also showed features which can be attributed to off-angle reflections from electron density depletions, thus corroborating the STEC observations. This observation suggests that the midlatitude ionosphere is more active even during geomagnetically quiet days than previously thought and that further studies are necessary. This is particularly relevant for the GNSS user community and related applications

    Multilocus Microsatellite Typing (MLMT) of Strains from Turkey and Cyprus Reveals a Novel Monophyletic L. donovani Sensu Lato Group

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    In eastern Mediterranean, leishmaniasis represents a major public health problem with considerable impact on morbidity and potential to spread. Cutaneous leishmaniasis (CL) caused by L. major or L. tropica accounts for most cases in this region although visceral leishmaniasis (VL) caused by L. infantum is also common. New foci of human CL caused by L. donovani complex strains were recently described in Cyprus and Turkey. Herein we analyzed Turkish strains from human CL foci in Çukurova region (north of Cyprus) and a human VL case in Kuşadasi. These were compared to Cypriot strains that were previously typed by Multilocus Enzyme Electrophoresis (MLEE) as L. donovani MON-37. Nevertheless, they were found genetically distinct from MON-37 strains of other regions and therefore their origin remained enigmatic. A population study was performed by Multilocus Microsatellite Typing (MLMT) and the profile of the Turkish strains was compared to previously analyzed L. donovani complex strains. Our results revealed close genetic relationship between Turkish and Cypriot strains, which form a genetically distinct L. infantum monophyletic group, suggesting that Cypriot strains may originate from Turkey. Our analysis indicates that the epidemiology of leishmaniasis in this region is more complicated than originally thought

    A Novel Form of Memory for Auditory Fear Conditioning at a Low-Intensity Unconditioned Stimulus

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    Fear is one of the most potent emotional experiences and is an adaptive component of response to potentially threatening stimuli. On the other hand, too much or inappropriate fear accounts for many common psychiatric problems. Cumulative evidence suggests that the amygdala plays a central role in the acquisition, storage and expression of fear memory. Here, we developed an inducible striatal neuron ablation system in transgenic mice. The ablation of striatal neurons in the adult brain hardly affected the auditory fear learning under the standard condition in agreement with previous studies. When conditioned with a low-intensity unconditioned stimulus, however, the formation of long-term fear memory but not short-tem memory was impaired in striatal neuron-ablated mice. Consistently, the ablation of striatal neurons 24 h after conditioning with the low-intensity unconditioned stimulus, when the long-term fear memory was formed, diminished the retention of the long-term memory. Our results reveal a novel form of the auditory fear memory depending on striatal neurons at the low-intensity unconditioned stimulus

    The Role of Host Genetics in Susceptibility to Influenza: A Systematic Review

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    Background: The World Health Organization has identified studies of the role of host genetics on susceptibility to severe influenza as a priority. A systematic review was conducted to summarize the current state of evidence on the role of host genetics in susceptibility to influenza (PROSPERO registration number: CRD42011001380). Methods and Findings: PubMed, Web of Science, the Cochrane Library, and OpenSIGLE were searched using a pre-defined strategy for all entries up to the date of the search. Two reviewers independently screened the title and abstract of 1,371 unique articles, and 72 full text publications were selected for inclusion. Mouse models clearly demonstrate that host genetics plays a critical role in susceptibility to a range of human and avian influenza viruses. The Mx genes encoding interferon inducible proteins are the best studied but their relevance to susceptibility in humans is unknown. Although the MxA gene should be considered a candidate gene for further study in humans, over 100 other candidate genes have been proposed. There are however no data associating any of these candidate genes to susceptibility in humans, with the only published study in humans being under-powered. One genealogy study presents moderate evidence of a heritable component to the risk of influenza-associated death, and while the marked familial aggregation of H5N1 cases is suggestive of host genetic factors, this remains unproven. Conclusion: The fundamental question ‘‘Is susceptibility to severe influenza in humans heritable?’ ’ remains unanswered. No
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